General Cell Lines and Cell Cultures
ATCC Pseudomonas aeruginosa; Strain PAO1-LAC; genomic DNA
Genomic DNA from Pseudomonas aeruginosa strain PAO1-LAC (ATCC 47085). This product can be used in PCR and other molecular biology applications.
Eurofins Discoverx ChemiScreen APJ Apelin Receptor Stable Cell Line, 2 vials. (HTS068C)
The ChemiScreen APJ Apelin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. apelin) based activation of AGTRL1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AGTRL1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of AGTRL1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Pfizer Pneumococcal; polysaccharide powder; Type 24 (24F) 10mg
Purified pneumococcal polysaccharide type 24F is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 24F can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Eurofins Discoverx PathHunter Rat DRD2S β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Rat DRD2S β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure DRD2S (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Influenza A virus (H1N1); A/Virginia/ATCC3/2009; RNA
Genomic RNA isolated from a preparation of cell lysate and supernatant from MDCK cells infected with Influenza A virus (H1N1) strain A/Virginia/ATCC3/2009 (ATCC VR-1738). This product was prepared using methods known to inactivate viruses. It is suitable for use in RT-PCR or other RNA-based procedures. The source organism and host cells are also available through the ATCC catalog.
ATCC UACC-3199; Breast Ductal Carcinoma; Human (Homo sapiens)
UACC-3199 is a cell line exhibiting epithelial-like morphology that was isolated in 1994 from a 58-year-old, White female with infiltrating ductal carcinoma of the breast metastatic to the left axillary lymph nodes. The patient had a family history of breast cancer and the cell line can be used for cancer research.
Amsbio LLC eLuCidate™ HEK 293, TLR3/ISRE Reporter Cell Line
eLuCidate™ HEK 293 TLR3/ISRE Reporter Cell Line
Eurofins Discoverx PathHunter U2OS SREBP2 Nuclear Translocation Cell Line, 2 vials. (93-0830C3)
The PathHunter U2OS SREBP2 Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the cholesterol biosynthesis pathway. This cell line enables assessment of ligand (e.g. 5'-UMP) based pathway activation via detection of resulting SREBP2 nuclear translocation. This product uses EFC technology. The included cell line overexpresses ProLabel-tagged SREBP2 and nuclear localized EA. Upon pathway activation, induced nuclear translocation of SREBP2 leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
Eurofins Discoverx PathHunter Cyno IL-8 (CXCR2) β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Cyno IL-8 (CXCR2) β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure CXCR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ATCC Haemophilus influenzae; Strain KW20; genomic DNA
Genomic DNA is isolated from Haemophilus influenzae strain Rd (ATCC 51907). This whole-genome sequenced product can be used in PCR and other molecular biology applications.
ABclonal Technology CCKAR Rabbit pAb
This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.
Eurofins Discoverx PathHunter U2OS mP2RY12 β-Arrestin Cell Line, 2 vials. (93-0695C3)
The PathHunter mP2RY6 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. UTP) based activation of mP2RY6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mP2RY6 and EA-tagged β-Arrestin-2. Activation of mP2RY6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.